How to achieve carbon neutrality in 2050? The debate is often polarised between the advocates of nuclear power and those of renewable energy. But doesn't the real answer lie in reconciling the two? Nuclear power to control costs and meet the climate challenge... But how? Which production mix for 2050? What are the mutually beneficial solutions and innovations in terms of nuclear power, EPR, SMR? How to ensure flexibility of choices? To best assess these issues, it is important to take into account the entire electric grid and to debate rationally. Challenges, technological innovations and future trends.